Adhesion Barriers
Scar tissue and adhesion are a normal, even necessary part of the wound healing process. But they can present a significant problem: Adhesions are a serious and frequent complication of surgical interventions and can require further surgery and hospitalisation. They can directly influence surgical outcome and success when they influence anatomic structures that are normally able to move freely in their tissue planes.
Adhesions normally occur at the site of the surgical procedure and frequently develop during the first three to five days after surgery.
A) Adhesion barrier gels, based on gel foam technology, used primarily for spinal applications and surgeries. Using barriers gels is the most common step to prevent adhesions. Barriers gels are the latest technology on the market: They separate opposing tissue planes and prevent the formation of fibrotic bands.
A clinical relevant example is lumbar spine surgery, in which adhesions may lead to recurrent back pain and/or leg pain and associated physical impairment of the patient. A re-operation may be required in some instances. This scenario is referred to as failed back surgery syndrome (FBSS).
EMCM has in its portfolio a marked biocompatible, resorbable gel that provides a physical barrier to inter-tissue adhesions. This is achieved by inhibiting fibroblast migration onto and around neural or tendinous structures.
Product Classification: CE marked Medical Device.
B) Rebasol, an anti-adhesive gel that prevents the formation of postoperative adhesions without any adverse effects on wound healing, is being developed. Rebasol's composition is innovative. It is a bioresorbable product consisting of ultra-pure alginate and poly-dextran sulphate. The muco-adherent properties of the gel allow it to remain in place even in gravitationally dependent areas. The product will also be easy to apply in both laparotomy and laparoscopy procedures and will be able to achieve a broad coverage of anatomic sites to prevent postoperative adhesion formation.
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